Amoxiclav 2x 500+125 mg N14 tablets

Amoxiclav, 625 mg film-coated tablets

Amoxiclav, international non-proprietary name: Amoxicillin, Clavulanic acid

Composition of Amoxiclav

Active ingredient: Each tablet contains 500 mg amoxicillin (as trihydrate) and 125 mg clavulanic acid (as potassium salt).

Indications for use

Amoxiclav is indicated in adults and children for the treatment of the following infections:
– Infections of the upper respiratory tract: sinusitis, otitis media, tonsillitis
– Infections of the lower respiratory tract: exacerbation of chronic bronchitis, pneumonia
– Infections of the genitourinary tract: cystitis, urethritis, pyelonephritis, infections of the female genital organs
– Infections of the skin and soft tissues: cellulitis, bite wounds, abscesses
– Infections of bones and joints: osteomyelitis
– Odontogenic infections and mixed infections: periodontitis, cellulitis, sepsis, etc.

Contraindications

High sensitivity to amoxicillin, clavulanic acid, or other beta-lactam antibiotics; history of anaphylactic reactions to these preparations; liver damage and/or jaundice with amoxicillin/clavulanic acid; severe liver and kidney failure.

Use during pregnancy and lactation

During pregnancy, it is used only in important cases. It may be used during lactation, but diarrhea and fungal infection may develop in the child. Both components pass into breast milk.

Use in pediatrics

In children with body weight less than 40 kg, suspension or another suitable dosage form is recommended. In children under 6 years of age, suspension is preferred. There is no clinical information on the use in children under 2 years of age at a dose of 40 mg/10 mg/kg/day.

Effect on the ability to drive vehicles and operate other potentially dangerous machinery

It is not recommended to drive vehicles or work with other machinery in cases such as dizziness, seizures, and allergic reactions.

How to take Amoxiclav

Tablets should be taken before meals.
Adults and children over 40 kg: 1 tablet 3 times a day.
In patients with impaired kidney function, the dose should be adjusted.
Creatinine clearance:
– 10–30 ml/min – 1 tablet 2 times a day
– <10 ml/min – 1 tablet 1 time a day
– Hemodialysis – 1 tablet every 24 hours + an additional dose during dialysis and after it

Recommended maximum duration of therapy: 14 days. Liver function should be monitored regularly.