Anaferon 25 ml Children’s Drops

Anaferon homeopathic drops for oral use in children

Anaferon composition

In 1 ml of solution there are 0.006 g* of affinity-purified antibodies against human gamma interferon. Excipients: maltitol, glycerol, potassium sorbate, anhydrous citric acid, purified water. *It is not possible to assess the administered composition in the form of a mixture of three active aqueous dilutions diluted 10012, 10030, 10050 times respectively, which makes it technically impossible to study its pharmacokinetics.

Indications for use

For children, treatment of acute respiratory tract infections during the period from 1 month to 3 years of age.

Contraindications

Increased individual sensitivity to the components of the medicinal product. Child age up to 1 month: fructose intolerance (due to the increased maltitol content in the composition).

Use during pregnancy and lactation

The safety of Anaferon use has not been studied; no data are available.

Anaferon dosage and method of use

For 1 dose: 10 drops (the drops are measured into a spoon). In the first days of treatment: on the first 2 hours, take 10 drops every 30 minutes; then, for the remaining time, take 10 drops 3 more times, again with a 30-minute interval between doses. From the 2nd to the 5th day of treatment: take 10 drops 3 times a day, each time. The medicine should be taken outside of meals. In the first days, it should be taken after 15 minutes. The first 5 doses of the medicine should be given between the child’s feedings, either with food or with liquid.

Pharmacological properties

Pharmacodynamics Based on preclinical studies and the results of clinical trials, the effectiveness of the medicinal product against influenza viruses, and simple herpes viruses types 1 and 2 (labial herpes, genital herpes), as well as other herpes viruses (chickenpox, infectious mononucleosis), and rotavirus has been proven. The product reduces the concentration of the virus in damaged tissues, affects the system of endogenous interferons and cytokines that bind to them, induces the formation of endogenous “early” interferons (IFNα/β) and gamma-interferon (IFNγ), and stimulates the cellular immune response. It increases the production of antibodies (including secretory IgA), activates the functions of T-effectors and T-helpers (Th), normalizes their interaction, and increases the functional reserve of Th and other cells involved in the response. It plays the role of an inducer of mixed Th1 and Th2 involved in the response: increases the formation of cytokines Th1 (IFNγ, IL-2) and Th2 (IL-4, IL-10), restores (modulates) the Th1/Th2 balance. It increases the functional activity of natural killer cells (NK cells) and phagocytes. Pharmacokinetics Due to the sensitivity of modern physicochemical analysis methods (gas-liquid chromatography, high-performance liquid chromatography, liquid chromatography-mass spectrometry), the preparation’s biological distribution in body fluids, organs, and tissues

Special instructions and precautions

Because the medicinal product contains maltitol, it should not be prescribed to patients with congenital fructose intolerance.

Interactions with other medicinal products

No incompatibility with other medicinal products has been recorded.

Side effects

Possible are reactions of increased individual sensitivity to the components of the medicinal product.